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Product Details
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Flammability and Explosibility |
Notclassified |
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General Description |
5-Chloro-1-(4-piperidyl)-2-benzimidazolinone is a 2-benzimidazolone derivative. It exhibits anti-nauseant properties. |
InChI:InChI=1/C12H14ClN3O/c13-8-1-2-11-10(7-8)15-12(17)16(11)9-3-5-14-6-4-9/h1-2,7,9,14H,3-6H2,(H,15,17)
While mu opioid receptor (MOR) agonists ...
The present invention relates to novel M...
The present invention relates to novel M...
In our continuing effort to identify CGR...
4-(5-chloro-2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidine-1-carboxylic acid ethyl ester
![5-chloro-1-(piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one](/upload/2026/7/a041e4dd-013e-4a08-a1da-b552e51b6860.png)
5-chloro-1-(piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
| Conditions | Yield |
|---|---|
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With
sodium hydroxide;
for 8h;
Heating;
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96% |
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With
sodium hydroxide;
at 100 ℃;
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|
|
With
ammonium chloride;
In
water;
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4-(4-chloro-2-nitro-anilino)-piperidine-1-carboxylic acid ethyl ester
5-chloro-1-(piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
| Conditions | Yield |
|---|---|
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Multi-step reaction with 3 steps
1: Zn; aq. HCl / methanol / 50 °C
2: acetonitrile
3: aq. NaOH / 100 °C
With
hydrogenchloride; sodium hydroxide; zinc;
In
methanol; acetonitrile;
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|
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Multi-step reaction with 3 steps
1: 93 percent / H2 / Raney Ni / ethanol; tetrahydrofuran / 1 h / Ambient temperature
2: 90 percent / Et3N / CH2Cl2 / 0.5 h / 0 °C
3: 96 percent / 10percent NaOH / 8 h / Heating
With
sodium hydroxide; hydrogen; triethylamine;
nickel;
In
tetrahydrofuran; ethanol; dichloromethane;
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4-(5-chloro-2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidine-1-carboxylic acid ethyl ester
ethyl 4-aminopiperidine-1-carboxylate
ethyl 4-[(2-amino-4-chlorophenyl)amino]piperidine-1-carboxylate
4-(4-chloro-2-nitro-anilino)-piperidine-1-carboxylic acid ethyl ester
axamozide
1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-5-chloro-1,3-dihydro-benzoimidazol-2-one
1-[1-(4-(4-fluorophenyl)-tetrahydro-2-furylmethyl)-4-piperidyl]-5-chloro-benzimidazolin-2-one maleate
5-chloro-1-{1-[4-(4-fluoro-phenyl)-4-phenyl-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one
