1997387-43-5

  • Product Name1-((S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl)-3-((S)-1-(thiophen-3-yl)propan-2-yl)urea
  • Molecular Weight361.508
  • Purity99%
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Product Details

Quick Details

  • CasNo: 1997387-43-5
  • Purity: 99%

Factory Sells Best Quality 1-((S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl)-3-((S)-1-(thiophen-3-yl)propan-2-yl)urea 1997387-43-5 with ISO standards

  • Molecular Formula:C19H27N3O2S
  • Molecular Weight:361.508
  • Boiling Point:583.8±50.0 °C(Predicted) 
  • PKA:10.06±0.15(Predicted) 
  • Density:1.169±0.06 g/cm3(Predicted) 

1997387-43-5 Relevant articles

MU OPIOID RECEPTOR MODULATORS

-

Paragraph 0416; 0472-0477, (2018/07/31)

Described herein, inter alia, are compos...

Synthesis of Enantiopure PZM21: A Biased Agonist of the Mu-Opioid Receptor

Perrey, David,Zhang, Dehui,Nguyen, Thuy,Carroll, F. Ivy,Ko, Mei-Chuan,Zhang, Yanan

, p. 4006 - 4012 (2018/07/30)

PZM21 (1) was recently reported as a bia...

MU OPIOID RECEPTOR MODULATORS

-

Paragraph 0424-0429, (2017/01/26)

Described herein, inter alia, are compos...

1997387-43-5 Process route

4-nitrophenyl (RS)-[1-(thiophen-3-yl)propan-2-yl]carbamate

4-nitrophenyl (RS)-[1-(thiophen-3-yl)propan-2-yl]carbamate

(S)-4-[3-amino-2-(dimethylamino)propyl]phenol dihydrochloride
2007916-74-5

(S)-4-[3-amino-2-(dimethylamino)propyl]phenol dihydrochloride

1-[(S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-((R)-1-(thiophen-3-yl)propan-2-yl)urea
1997387-43-5

1-[(S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-((R)-1-(thiophen-3-yl)propan-2-yl)urea

1-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-[(2S)-1-(thiophen-3-yl)propan-2-yl]urea
1997387-43-5

1-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-[(2S)-1-(thiophen-3-yl)propan-2-yl]urea

Conditions
Conditions Yield
With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 20h; Overall yield = 70 %; Overall yield = 100 mg; Inert atmosphere;
With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 20h; Inert atmosphere;
4-nitrophenyl (RS)-[1-(thiophen-3-yl)propan-2-yl]carbamate

4-nitrophenyl (RS)-[1-(thiophen-3-yl)propan-2-yl]carbamate

(S)-4-[3-amino-2-(dimethylamino)propyl]phenol dihydrochloride
2007916-74-5

(S)-4-[3-amino-2-(dimethylamino)propyl]phenol dihydrochloride

1-[(S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-((R)-1-(thiophen-3-yl)propan-2-yl)urea
1997387-43-5

1-[(S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-((R)-1-(thiophen-3-yl)propan-2-yl)urea

1-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-[(2S)-1-(thiophen-3-yl)propan-2-yl]urea
1997387-43-5

1-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-[(2S)-1-(thiophen-3-yl)propan-2-yl]urea

Conditions
Conditions Yield
With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 20h; Overall yield = 70 %; Overall yield = 100 mg; Inert atmosphere;
With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 20h; Inert atmosphere;

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