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Described herein, inter alia, are compos...
PZM21 (1) was recently reported as a bia...
Described herein, inter alia, are compos...
4-nitrophenyl (RS)-[1-(thiophen-3-yl)propan-2-yl]carbamate
(S)-4-[3-amino-2-(dimethylamino)propyl]phenol dihydrochloride
1-[(S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-((R)-1-(thiophen-3-yl)propan-2-yl)urea
1-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-[(2S)-1-(thiophen-3-yl)propan-2-yl]urea
| Conditions | Yield |
|---|---|
|
With
triethylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 20h;
Overall yield = 70 %; Overall yield = 100 mg;
Inert atmosphere;
|
|
|
With
triethylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 20h;
Inert atmosphere;
|
4-nitrophenyl (RS)-[1-(thiophen-3-yl)propan-2-yl]carbamate
(S)-4-[3-amino-2-(dimethylamino)propyl]phenol dihydrochloride
1-[(S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-((R)-1-(thiophen-3-yl)propan-2-yl)urea
1-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-[(2S)-1-(thiophen-3-yl)propan-2-yl]urea
| Conditions | Yield |
|---|---|
|
With
triethylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 20h;
Overall yield = 70 %; Overall yield = 100 mg;
Inert atmosphere;
|
|
|
With
triethylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 20h;
Inert atmosphere;
|
3-thiophene carboxaldehyde
(E)-3-(2-nitroprop-1-en-1-yl)thiophene
(S)-4-[3-amino-2-(dimethylamino)propyl]phenol dihydrochloride
(RS)-1-(thiophen-3-yl)propan-2-amine hydrochloride
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