117704-25-3

Factory Supply industrial standard Doramectin 117704-25-3 In Stock We supply high quality Doramectin (CAS 117704-25-3), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the Doramectin ?

Doramectin is white to off-white crystalline powder, while it's Molecular Formula is C50H74O14. Mutational biosynthetic antiparasitic antibiotic structurally related to the avermectins

What is the CAS number for Doramectin ?

The CAS number of Doramectin is 117704-25-3.

More information of Doramectin 117704-25-3 are:

What is Doramectin (117704-25-3) used for?

Doramectin is a novel avermectin with a cyclohexyl substituent on the previously inaccessible C-25 position of the molecule; the substitution was facilitated by mutational biosynthesis. The discovery of doramectin involved feeding carboxylic acids or their precursors to a fermentation of Streptomyces avermitilis that lacked branched-chain 2-oxo acid dehydrogenase activity, and then screening the resultant fermentation products for anthelmintic and ectoparasiticidal activity (89). Two dosage forms of doramectin have been developed for use as an endectocide on cattle, an injectable formulation for subcutaneous administration and a pouron formulation. An injectable formulation is also approved for use on pigs.

InChI:InChI=1/C50H74O14/c1-27-13-12-16-34-26-57-47-42(51)30(4)21-37(50(34,47)54)48(53)60-36-22-35(63-49(25-36)20-19-29(3)45(64-49)33-14-10-9-11-15-33)18-17-28(2)44(27)61-41-24-39(56-8)46(32(6)59-41)62-40-23-38(55-7)43(52)31(5)58-40/h12-13,16-17,19-21,27,29,31-33,35-47,51-52,54H,9-11,14-15,18,22-26H2,1-8H3/b13-12+,28-17+,34-16-/t27-,29-,31-,32-,35+,36-,37-,38-,39-,40-,41-,42+,43-,44?,45-,46?,47+,49+,50+/m0/s1

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