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Factory Sells Best Quality Diethylstilbestrol 56-53-1 with GMP standards We supply high quality Diethylstilbestrol (CAS 56-53-1), in stock, factory directly supply to clients, lower prices, more competitiveness.
Diethylstilbestrol is White solid, while it's Molecular Formula is C18H20O2. Diethylstilbestrol is a synthetic nonsteroidal estrogen that was formerly used in estrogenic hormone therapy (for menstrual disorders, postpartum breast engorgement, postcoital contraceptive, prevention of spontaneous abortion) and in chemotherapy of various cancers, including postmenopausal breast cancer and prostate cancer. It was also used in biomedical research and veterinary medicine (growth promoter for cattle and sheep; veterinary drug to treat estrogen deficiency disorders).
The CAS number of Diethylstilbestrol is 56-53-1.
More information of Diethylstilbestrol 56-53-1 are:
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Synonyms |
4,4'-Stilbenediol,a,a'-diethyl-, (E)- (8CI);4,4'-Stilbenediol, a,a'-diethyl-, trans- (4CI);Phenol, 4,4'-(1,2-diethyl-1,2-ethenediyl)bis-,(E)-;(E)-3,4-Bis(4-hydroxyphenyl)-3-hexene;(E)-4,4'-(1,2-Diethyl-1,2-ethenediyl)bisphenol;(E)-Diethylstilbestrol;4,4'-Dihydroxy-a,b-diethylstilbene;4,4'-Dihydroxydiethylstilbene;Agostilben;Antigestil;Bertrol;Bio-des;Bufon;Comestrol;Cyren;Cyren A;DEB;DES;DES (synthetic estrogen);Dawe's destrol;Di-Estryl;Diethylstilbestrol;Distilbene;Domestrol;Estrobene;Estromenin;Estrosyn;Fonatol;Hi-Bestrol;Microest;Milestrol;NSC 3070;Oestromensyl;Palestrol;Serral;Sexocretin;Sibol;Stilbetin;Stilboefral;Stilboestrol;Synthoestrin;Synthofolin;Syntofolin;trans-4,4'-Dihydroxy-a,b-diethylstilbene;trans-Diethylstilbestrol;trans-a,a'-Diethyl-4,4'-stilbenediol;a,a'-Diethyl-4,4'-stilbenediol;a,a'-Diethylstilbenediol; |
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CAS Number |
56-53-1 |
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Molecular Formula |
C18H20O2 |
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Molecular Weight |
268.356 |
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Density |
1.107 g/cm3 |
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Melting Point |
170-172 °C(lit.) |
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Boiling Point |
407.1 °C at 760 mmHg |
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Flash Point |
186.9 °C |
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HS CODE |
29072990 |
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PSA |
40.46000 |
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LogP |
4.82860 |
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Pka |
pKa 9.02(H2O t=25 I=0.025) (Uncertain) |
Diethylstilbestrol (DES) is a synthetic estrogen receptor agonist that was prescribed to pregnant women in the late 1930s. It was banned in 1971 because of possible links to increased risk of breast cancer in mothers along with congenital abnormalities and increased risk of cancer in offspring. DES is structurally related to, and is as potent as, estradiol in most assays, with a longer half-life. It has a relative binding affinity to sex hormone binding globulin (SHBG) of 0.2 compared to estradiol which has a relative binding affinity of 100. A concentration of 20 μM DES, displaces 30 ± 13% of 3H-estradiol from SHBG in serum.
InChI:InChI=1/C18H20O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,19-20H,3-4H2,1-2H3/b18-17-
Articles related to Diethylstilbestrol:
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Article |
Source |
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Diethylstilbestrol-scaffold-based pregnane X receptor modulators |
Hodnik, ?iga,Toma?i?, Tihomir,Smodi?, Domen,D'Amore, Claudio,Ma?i?, Lucija Peterlin,Fiorucci, Stefano,Kikelj, Danijel , p. 551 - 562 (2015/10/12) |
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THERAPEUTIC FOR HEPATIC CANCER |
- , (2011/02/18) |
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