154992-24-2

  • Product NameRU 58841 154992-24-2
  • Molecular FormulaC17H18F3N3O3
  • Molecular Weight369.343
  • Purity99%
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  • CasNo: 154992-24-2
  • Molecular Formula: C17H18F3N3O3
  • Purity: 99%

High Quality Chinese Manufacturer supply 154992-24-2 RU 58841 154992-24-2 We provide high quality RU 58841 (CAS 154992-24-2), at a very affordable prices to our customers.

1.What is the RU 58841 ?

RU-58841 is a non-steroidal antiandrogen that binds to the androgen receptor (Kd = 1.8, 1.1, 5.6, 1.3, and 1.4 nM for human, rat, mouse, hamster prostate, and hamster flank organ receptors, respectively). In vivo, topical administration of RU-58841 (1-100 μg per animal) reduces size of the flank organ without affecting sex organs in a dose-dependent manner in hamsters. It has no effect on sex organ weight in intact rats when administered percutaneously, subcutaneously, or orally at doses up to 1 mg per animal. RU-58841 (5% v/v) also induces hair regrowth in the bald frontal scalps of postpubertal stumptailed macaques, a model for male pattern baldness.

RU 58841, is a specific androgen receptor antagonist or anti-androgen, that has shown to have effect on hair growth.

2.What is the CAS number for RU 58841 ?

The CAS number of RU 58841 is 154992-24-2.

More information of RU 58841 154992-24-2 are:

CAS Number

154992-24-2

Density

1.397 g/cm3

Boiling Point

493.588 °C at 760 mmHg

Flash Point

252.313 °C

Vapor Pressure

1.47E-10mmHg at 25°C

Refractive Index

1.559

HS CODE

2933990090

PSA

84.64000

LogP

2.89968

Pka

15.09±0.10(Predicted)

3.What is the molecular formula of RU 58841 ?

The chemical formula of RU 58841 is C17H18F3N3O3 which containing 17 Carbon atoms,18 Hydrogen atoms,3 Fluorine atoms,3 Nitrogen atoms and 3 Oxygen atoms,and the molecular weight, and the molecular weight of RU 58841 is 369.343

4.What is RU 58841(154992-24-2)used for?

RU-58841 is a non-steroidal antiandrogen that binds to the androgen receptor (Kd = 1.8, 1.1, 5.6, 1.3, and 1.4 nM for human, rat, mouse, hamster prostate, and hamster flank organ receptors, respectively). In vivo, topical administration of RU-58841 (1-100 μg per animal) reduces size of the flank organ without affecting sex organs in a dose-dependent manner in hamsters. It has no effect on sex organ weight in intact rats when administered percutaneously, subcutaneously, or orally at doses up to 1 mg per animal. RU-58841 (5% v/v) also induces hair regrowth in the bald frontal scalps of postpubertal stumptailed macaques, a model for male pattern baldness.

InChI:InChI=1/C17H18F3N3O3/c1-16(2)14(25)23(15(26)22(16)7-3-4-8-24)12-6-5-11(10-21)13(9-12)17(18,19)20/h5-6,9,24H,3-4,7-8H2,1-2H3

Relevant articles related to RU 58841:

Article

Source

Alternative synthesis of the anti-baldness compound RU58841

Leonard, Matthew J.,Lingham, Anthony R.,Niere, Julie O.,Jackson, Neale R. C.,McKay, Peter G.,Huegel, Helmut M.

, p. 14143 - 14148 (2014/04/17)

5.High Quality Chinese Manufacturer supply 154992-24-2 RU 58841 154992-24-2

Hebei Zhaohe Chemical Technology Co., Ltd. is a quality supplier of RU 58841. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on RU 58841 154992-24-2.

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