4727-31-5

Factory Export Top Purity Kartogenin4727-31-5 4727-31-5 In Stock We supply high quality Kartogenin (CAS 4727-31-5), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the Kartogenin ?

Kartogenin is , while it's Molecular Formula is C20H15NO3. Kartogenin is a potent, selective, and non-cytotoxic downstream RUNX1 and RUNX2 modulator. Kartogenin causes mesenchymal stem cells found in joints to differentiate into chondrocyte cells that can build cartilage where it has been destroyed.

What is the CAS number for Kartogenin ?

The CAS number of Kartogenin is 4727-31-5.

More information of Kartogenin 4727-31-5 are:

What is Kartogenin (4727-31-5) used for?

Kartogenin potently induces differentiation of human mesenchymal stem cells into chondrocytes with an EC50 value of 100 nM. Kartogenin induces chondrogenesis by binding the actin-binding protein, filamin A, which disrupts its interaction with the transcription factor core-binding factor β subunit (CBFβ). When dissociated from filamin A, CBFβ translocates to the nucleus and forms a transcriptional complex with the runt-related transcription factor RUNX1, which enables chondrocyte differentiation. Kartogenin has been shown to promote cartilage repair in a mouse model of osteoarthritis and to protect against cytokine-induced damage in osteoarthritic bovine articular chondrocytes in vitro.

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How to get the best price on Kartogenin?

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